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★National Top Tier · Pituitary Tumor and Skull Base Tumor Center

Department of Neurosurgery

Led by Professors Wang Renzhi and Ma Wenbin, internationally renowned for endoscopic transnasal minimally invasive pituitary surgery

Department Introduction and Development History

The Department of Neurosurgery at Peking Union Medical College Hospital has a long history and is one of the earliest departments to engage in neurosurgery in China. As early as the 1930s, pioneers in Chinese neurosurgery, Professors Guan Songtao and Zhao Yicheng, conducted the first brain tumor surgeries at Peking Union Medical College Hospital. Subsequently, renowned neurosurgeons such as Professors Feng Chuanyi, Wang Weijun, and Yin Zhaoyan made significant contributions to the development and expansion of the neurosurgery department at Peking Union Medical College Hospital, actively promoting the advancement of neurosurgery in China.

Currently, the Department of Neurosurgery at Peking Union Medical College Hospital is divided into specialized groups focusing on sellar tumors, malignant tumors, spinal cord and spine, functional neurosurgery, skull base tumors, and acute critical care. The pituitary adenoma group is a specialty group that has performed over 8,000 pituitary adenoma surgeries, achieving treatment outcomes that are internationally advanced and domestically leading. Based on the overall advantages of the department and its excellent diagnostic and therapeutic results, the Pituitary Tumor Neurosurgery Treatment Center was established in 2002.

Century-Old Heritage · Premier Specialties

Academic Standing & Clinical Excellence

A key national discipline in neurosurgery. Collaborating with the Endocrinology Department to establish a world-renowned multidisciplinary treatment center (MDT) for pituitary tumors, excelling in individualized comprehensive treatment for endoscopic transnasal minimally invasive resection of pituitary adenomas, craniopharyngiomas, skull base meningiomas, vestibular schwannomas, and gliomas.

National Centers & Research Platforms

  • 🏛Key Discipline of Neurosurgery, Ministry of Education
  • 🏛Multidisciplinary Diagnosis and Treatment Center for Pituitary Adenomas (MDT)
  • 🏛Core Unit of the National Clinical Research Center for Neurological Diseases
  • 🏛Standardized Diagnosis and Treatment Demonstration Base for Gliomas

Core Indications & Conditions Treated

01Pituitary adenomas (acromegaly, Cushing's disease, prolactinomas, non-functioning adenomas)
02Craniopharyngiomas and germ cell tumors in the sella
03Gliomas (high-grade glioblastomas and low-grade gliomas)
04Skull base meningiomas, vestibular schwannomas, and trigeminal schwannomas
05Brain metastases and central nervous system lymphomas
06Chiari malformation (cerebellar tonsillar herniation), atlantoaxial dislocation, and cranio-cervical junction anomalies
07Intradural tumors and intramedullary and extramedullary spinal tumors
08Cranial trauma and acute critical care for intracerebral hemorrhage

Clinical Strengths & Advanced Capabilities

Routine use of endoscopic transsphenoidal minimally invasive approaches, multimodal neuro-navigation, intraoperative MRI, and intraoperative neurophysiological monitoring, fully balancing complete tumor resection with the preservation of neurological function.

1

Endoscopic transnasal minimally invasive resection of complex invasive pituitary adenomas, sellar meningiomas, and craniopharyngiomas, with minimal trauma and clear surgical field

2

Maximal safe resection of gliomas in functional areas under awake anesthesia combined with intraoperative neurophysiological monitoring

3

Minimally invasive precise surgical approach design for skull base tumors guided by multimodal imaging fusion technology (MRI + PET + DTI)

4

Integrated management of gliomas based on molecular pathological typing, including surgery, temozolomide chemotherapy, radiotherapy, and tumor treating fields (TTFields)

5

Minimally invasive decompression of the posterior cranial fossa and atlantoaxial stabilization and fusion for cranio-cervical junction anomalies

Lead Physicians & Specialists

26 Expert
WR

Wang Renzhi

Chief Physician, Professor, Doctoral Supervisor

🏅 Former Chair of Neurosurgery, PUMCH · Director of Pituitary MDT Center

Core Indications & Conditions Treated

Transsphenoidal Minimally Invasive Surgery for Pituitary AdenomaInvasive Giant Pituitary AdenomaCraniopharyngiomaClival Chordoma and Meningioma

Pioneer of endoscopic endonasal pituitary surgery in China. Internationally renowned master surgeon in invasive pituitary adenomas and craniopharyngiomas.

XZ

Xu Zhiqin

Chief Physician, Professor, Doctoral Supervisor

Core Indications & Conditions Treated

Endonasal Endoscopic Transsphenoidal Resection of Pituitary AdenomaSella Turcica MeningiomaEndoscopic Repair of Cerebrospinal Fluid RhinorrheaCraniopharyngioma

Expert in endoscopic endonasal resection of pituitary macroadenomas/microadenomas, sellar meningiomas, and skull base reconstruction.

MW

Ma Wenbin

Chief Physician, Professor, Doctoral Supervisor

🏅 Director of Neurosurgery, PUMCH · President, Chinese Society of Neuro-Oncology (Glioma Committee)

Core Indications & Conditions Treated

Microsurgery and Comprehensive Treatment of GliomasIntraoperative Awake Functional Area Brain Tumor ResectionBrain Metastases and MeningiomasTumor Treating Fields (TTFields) Therapy

Director of Neurosurgery at PUMCH and national leader in neuro-oncology, specializing in awake craniotomy for eloquent-area gliomas and multimodal therapy.

GJ

Gao Jun

Chief Physician, Professor, Doctoral Supervisor

Core Indications & Conditions Treated

Chiari malformation with cerebellar tonsillar herniationAtlantoaxial Dislocation and Craniovertebral Junction MalformationsIntradural Spinal Cord TumorsPosterior Fossa Tumors

Specializes in craniovertebral junction anomalies, Chiari malformation posterior fossa decompression, atlantoaxial fusion, and spinal cord tumors.

ZY

Zhao Yuanli

Chief Physician, Professor, Doctoral Supervisor

Core Indications & Conditions Treated

Surgical Treatment of Cerebrovascular Diseases (Intracranial Aneurysm Clipping, Arteriovenous Malformations)Surgical Bypass for Moyamoya DiseaseMicrosurgery for Acoustic Neuroma

Senior neurosurgeon specializing in intracranial aneurysm clipping, AVM resection, bypass for Moyamoya disease, and acoustic neuroma microsurgery.

RZ

Ren Zuyuan

Chief Physician, Professor

Core Indications & Conditions Treated

Deep Brain TumorsIntracranial AneurysmArteriovenous MalformationBrainstem TumorsCarotid Endarterectomy for Ischemic Cerebrovascular DiseaseFunctional Neurosurgery and Surgical Treatment of Spinal Tumors

Dr. Ren Zuyuan is a Chief Physician and Professor in Neurosurgery, specializing in the management of deep brain tumors, intracranial aneurysms, arteriovenous malformations, and brainstem tumors.

LW

Lian Wei

Chief Physician, Professor

Core Indications & Conditions Treated

Diagnosis and Management of Pituitary Adenomas and Minimally Invasive Surgical TreatmentHyperprolactinemiaGigantismAcromegalyCushing's SyndromeComprehensive Diagnosis and Treatment of Various Types of Pituitary Adenomas Including Thyroid-Stimulating Hormone Adenomas

Dr. Lian Wei is a Chief Physician and Professor in Neurosurgery, focusing on the diagnosis and minimally invasive surgical treatment of pituitary adenomas and related conditions.

XB

Xing Bing

Chief Physician, Professor, Doctoral Supervisor

Core Indications & Conditions Treated

Minimally Invasive Surgical Treatment of Pituitary AdenomasAcromegalyCushing's SyndromeComprehensive Diagnosis and Treatment of Various Types of Pituitary Adenomas Including Thyroid-Stimulating Hormone AdenomasPituitary AbscessDiabetes Insipidus

Dr. Xing Bing is a Chief Physician and Professor in Neurosurgery, specializing in minimally invasive surgical treatment of pituitary adenomas and comprehensive management of various pituitary disorders.

YY

Yang Yi

Chief Physician, Professor

Core Indications & Conditions Treated

Acoustic NeuromaMeningiomaPituitary AdenomaCraniopharyngioma

Dr. Yang Yi is a Chief Physician and Professor in Neurosurgery, with expertise in the diagnosis and treatment of acoustic neuromas, meningiomas, pituitary adenomas, and craniopharyngiomas.

SZ

Su Zhangbao

Chief Physician, Professor

Core Indications & Conditions Treated

Microsurgery for Complex Intracranial and Spinal DisordersTranssphenoidal Surgery for Pituitary Tumors and Management of Difficult CasesEpilepsy Surgery

Dr. Su Zhangbao is a Chief Physician and Professor in Neurosurgery, specializing in microsurgery for complex intracranial and spinal disorders, as well as transsphenoidal surgery for pituitary tumors.

LY

Li Yongning

Chief Physician, Professor

Core Indications & Conditions Treated

Cranial TumorsSpinal Cord and Spine DiseasesHemifacial SpasmTreatment of Trigeminal Neuralgia

Dr. Li Yongning is a Chief Physician and Professor in Neurosurgery, focusing on cranial tumors, spinal cord diseases, hemifacial spasm, and trigeminal neuralgia.

DW

Dou Wanchen

Chief Physician, Professor

Core Indications & Conditions Treated

Epilepsy Due to Causes such as Hippocampal SclerosisCavernous HemangiomaAnaplastic AstrocytomaCortical DysplasiaExpertise in Diagnosis and Treatment of Epilepsy Due to Heterotopia and Hypothalamic HamartomasHemifacial Spasm

Dr. Dou Wanchen is a Chief Physician and Professor in Neurosurgery, specializing in epilepsy and other functional neurosurgical conditions. He has significant experience in diagnosing and treating complex neurosurgical diseases.

YZ

Yang Zhong

Associate Chief Physician, Associate Professor

Core Indications & Conditions Treated

Spinal Neurosurgery and Related Pain ManagementSpinal TumorsIntradural and Extradural TumorsSpinal Cord InjurySpinal Vascular DiseasesCranio-Cervical Junction Malformations and Chiari Malformation with Syringomyelia

Dr. Yang Zhong is an Associate Chief Physician and Associate Professor in Neurosurgery, with extensive clinical experience in spinal neurosurgery and pain management, particularly in spinal tumors and spinal cord injuries.

WL

Wang Ligen

Associate Chief Physician, Associate Professor

Core Indications & Conditions Treated

Cranial and Brain InjuriesAdequate Understanding and Treatment of Spinal Cord InjuryCranial TumorsSpinal Canal TumorsTreatment of Cerebrovascular DiseasesTreatment of Other Cranial and Brain Diseases

Dr. Wang Ligen is an Associate Chief Physician and Associate Professor in Neurosurgery, specializing in cranial and brain injuries, spinal cord injury treatment, and cranial tumors.

YY

Yao Yong

Chief Physician, Professor

Core Indications & Conditions Treated

Endonasal Endoscopic Surgery for Various Pituitary TumorsRecurrent Pituitary Growth Hormone Adenomas, etc.Germ Cell TumorsCraniopharyngiomaSurgical Treatment of Chordoma and Other Sellar Region DiseasesMultidisciplinary Collaboration for Comprehensive Diagnosis and Treatment of Complex Refractory Pituitary Adenomas

Dr. Yao Yong is a Chief Physician and Professor in Neurosurgery, specializing in endonasal endoscopic surgery for pituitary tumors and recurrent adenomas.

DK

Deng Kan

Associate Chief Physician, Lecturer

Core Indications & Conditions Treated

Sella Turcica TumorsSkull Base and Junctional TumorsCerebrovascular DiseaseDiagnosis and Treatment of Posterior Fossa TumorsExpertise in NeuroendoscopyIntraoperative MRI

Dr. Deng Kan is an Associate Chief Physician and Lecturer specializing in neurosurgery, particularly in the treatment of sella turcica tumors and cerebrovascular diseases.

GY

Guo Yi

Chief Physician, Associate Professor

Core Indications & Conditions Treated

Functional NeurosurgerySurgical Treatment of Brain TumorsSignificant Achievements in Neuroregulatory Techniques for Treating Movement Disorders

Dr. Guo Yi is a Chief Physician and Associate Professor specializing in functional neurosurgery and the surgical treatment of brain tumors.

WJ

Wei Junji

Chief Physician, Professor

Core Indications & Conditions Treated

Pituitary AdenomaIntracranial TumorsCranial and brain injuriesCerebrovascular DiseaseHydrocephalusSevere Infections

Dr. Wei Junji is a chief physician and professor specializing in neurosurgery, particularly in pituitary adenomas and cerebrovascular diseases, with extensive leadership roles in various medical associations.

FM

Feng Ming

Chief Physician, Professor

Core Indications & Conditions Treated

Expertise in the Treatment of Various Pituitary TumorsEspecially Cushing's Disease. [Pituitary Tumors Include: Non-Functional Pituitary Adenomas]Growth Hormone-Secreting Pituitary AdenomaProlactin-Secreting Pituitary AdenomaAdrenocorticotropic Hormone Pituitary AdenomaThyroid-Stimulating Hormone Pituitary Adenoma

Dr. Feng Ming is a Chief Physician and Professor specializing in the treatment of pituitary tumors, particularly Cushing's disease, with extensive experience in microsurgical techniques.

WY

Wang Yu

Chief Physician, Professor

Core Indications & Conditions Treated

Diagnosis and Surgical-Based Comprehensive Treatment of Central Nervous System Malignancies and Brain MetastasesEspecially in including new surgical techniquesTargeted TherapyNew Therapies Including ImmunotherapyRich Experience in New Clinical Research Areas

Dr. Wang Yu is a Chief Physician and Professor in the Department of Neurosurgery, specializing in the diagnosis and surgical treatment of central nervous system malignancies and brain metastases.

BX

Bao Xinjie

Chief Physician, Professor

Core Indications & Conditions Treated

Pituitary AdenomaCraniopharyngiomaMeningiomaAcoustic NeuromaHemifacial SpasmTrigeminal Neuralgia. 1

Dr. Bao Xinjie is a Chief Physician and Professor specializing in neurosurgery, particularly in the management of pituitary adenomas, craniopharyngiomas, meningiomas, and acoustic neuromas.

ZX

Zhang Xiao

Associate Chief Physician, Lecturer

Core Indications & Conditions Treated

Shunt Surgery for HydrocephalusThird Ventriculostomy for Obstructive HydrocephalusBurr Hole Drainage Surgery for Chronic Subdural HematomaTraditional and Minimally Invasive Surgical Treatment of Intracerebral HemorrhageDecompressive craniectomyVentricular Drainage

Dr. Zhang Xiao is an associate chief physician in neurosurgery, focusing on shunt surgery for hydrocephalus, third ventriculostomy, and minimally invasive surgical treatments for intracerebral hemorrhage.

LZ

Li Zhimin

Attending Physician

Core Indications & Conditions Treated

Spinal Cord and Spine-Related DiseasesIntradural TumorsMeningiomaCongenital TumorsIntradural Spinal TumorsGliomas, etc.

Dr. Li Zhimin is an attending physician in neurosurgery, focusing on spinal cord and spine-related diseases.

LQ

Liu Qi

Attending Physician

Core Indications & Conditions Treated

1) Cerebrovascular Diseases. Cerebral AneurysmCerebrovascular MalformationsCerebral Arteriovenous FistulaBasilar Artery StenosisMiddle Cerebral Artery StenosisCarotid Artery Stenosis

Dr. Liu Qi is an attending physician in neurosurgery, specializing in cerebrovascular diseases, including cerebral aneurysms and arteriovenous malformations.

ZY

Zhang Yi

Attending Physician

Core Indications & Conditions Treated

Pituitary AdenomaCraniopharyngiomaSella MeningiomaEndoscopic and Craniotomy Treatment of Germ Cell Tumors and Other Sellar Region DiseasesComprehensive medical guidance for diseases related to pituitary stalk thickening such as germ cell tumorsMeningioma

Dr. Zhang Yi is an attending physician in neurosurgery, specializing in the treatment of pituitary adenomas and craniopharyngiomas.

GX

Guo Xiaopeng

Attending Physician

Core Indications & Conditions Treated

Diagnosis and Treatment of Common Neurological DiseasesClinical Treatment of Brain TumorsBrain GliomaMeningiomaPituitary AdenomaBrain Metastases and Related Conditions. Supported by the National Center for Difficult Diseases at Peking Union Medical College Hospital

Dr. Guo Xiaopeng is an attending physician in neurosurgery, with expertise in the clinical treatment of brain tumors, including gliomas and meningiomas. He has a joint doctoral degree from Peking Union Medical College and Harvard Medical School, and has published extensively in the field.

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