Patient SupportIndependent support for PUMCH patients
English
★National Top Tier · Center for Rare Diseases and Neonatology

Department of Pediatrics

Led by Professor Song Hongmei, independently developed a national class II new orphan drug to address medication challenges for children with rare diseases.

Department Introduction and Development History

The Department of Pediatrics at Peking Union Medical College Hospital leverages the overall advantages of multidisciplinary collaboration in a comprehensive hospital, enjoying a prestigious reputation in the diagnosis and treatment of difficult diseases within the pediatric system in China; it has outstanding characteristics in the treatment of kidney diseases and autoimmune diseases; the neonatal specialty is robust, relying on the perinatal center of the hospital, leading in the emergency rescue and transport of critically ill neonates, as well as the management and follow-up of preterm infants, especially those with extremely low birth weight; in collaboration with the Genetics Laboratory of the Institute of Basic Medical Sciences and the Obstetrics and Gynecology Department of the hospital, a genetic center has been established to provide prenatal genetic diagnosis and counseling for various genetic diseases; other specialties such as gastroenterology, respiratory medicine, and hematology are also rapidly developing; the Pediatric Intensive Care Unit (PICU) collaborates with departments such as Cardiothoracic Surgery, Neurosurgery, and Orthopedics, responsible for the monitoring and treatment of surgical patients; it was one of the first in the country to implement systematic management and early intervention for high-risk infants, accumulating rich early education experience and continuously improving, making the Department of Pediatrics at Peking Union Medical College Hospital a truly comprehensive pediatric service provider.

In 1998, Professor Zhou Huakang received the first China Naito International Childcare Award.

In 2004, Professor Bao Xiulan received the fourth China Naito International Childcare Award.

In recent years, the following medical achievement awards have been received by Peking Union Medical College Hospital:

The first domestic case diagnosed with congenital metabolic disorder: Methylmalonic Acidemia won the third prize for medical achievements in 1986.

Successful rescue of a rare acute encephalopathy complicated by hepatic steatosis, Reye's syndrome won the second prize for medical achievements in 1987.

Successful rescue of a 1650g preterm infant complicated by Hyaline Membrane Disease, Necrotizing Enterocolitis, and Sepsis won the second prize for medical achievements in 1988.

Satisfactory results in the diagnosis and treatment of acute glomerulonephritis won the third prize for medical achievements in 1988.

Rescue of two extremely low birth weight infants with multiple complications won the second prize for medical achievements in 1989.

Successful treatment of refractory infant diarrhea won the third prize for medical achievements in 1989.

Successful collaborative treatment of pediatric myasthenia gravis won the first prize for medical achievements in 1990.

Successful rescue of preterm infants with Hyaline Membrane Disease and persistent fetal circulation won the second prize for medical achievements in 1990.

Treatment of severe refractory nephrotic syndrome won the third prize for medical achievements in 1991.

Resection of thymoma in a 4-year-old child with myasthenia gravis won the second prize for medical achievements in 1992.

Successful rescue of a twin preterm infant at 30 weeks gestation won the third prize for medical achievements in 1992.

Successful diagnosis and treatment of two cases of ectopic ACTH-secreting tumors in children won the second prize for medical achievements in 1993.

Success rate and prognosis of preterm infant rescue in 1993 won the third prize for medical achievements in 1993.

Diagnosis of 10 rare and difficult single-gene genetic diseases won the third prize for medical achievements in 1994.

Rescue of critically ill neonates won the second prize for medical achievements in 1996.

High-frequency oscillatory ventilation treatment for 17 cases of neonatal respiratory failure won the third prize for medical achievements in 2000.

Care for 115 extremely low birth weight infants won the third prize for medical achievements in 2000.

Innovative and meticulous efforts to improve the rescue level of extremely low birth weight infants won the second prize for medical achievements in 2001.

Leveraging the advantages of a comprehensive hospital to achieve top-tier levels in the diagnosis and treatment of difficult and critical conditions won the third prize for medical achievements in 2002.

Establishment of a green channel for the transport of critically ill neonates won the third prize for medical achievements in 2002.

Rescue of critically ill neonates won the 1996 China Academy of Medical Sciences Medical Achievement Award.

(1) Research projects undertaken since 2000:

1. Key clinical project of the Ministry of Health: Prevention and treatment of respiratory failure in low birth weight infants to improve quality of life. 1997–2000 Zhao Shimin et al. (770,000).

2. Doctoral research fund from the Education Commission: Experimental study on NO treatment for pulmonary hypertension caused by meconium aspiration syndrome. 1998-2001 Xu Jingzhen et al. (40,000).

3. Research fund from the Academy of Medical Sciences: Genetic analysis of Glycogen Storage Disease Type I. 2000-2002 Qiu Zhengqing et al. (30,000).

4. Research fund from Peking Union Medical College Hospital: Clinical and laboratory studies on neonatal thrombopoietin. 2000–2003 Ding Guofang et al. (30,000).

5. Doctoral research fund from the Education Commission: Study on the effects of lipoprotein-induced proliferation of glomerular mesangial cells and intracellular signaling pathways. 2001–2003 Wei Min et al. (40,000).

6. Personnel Department Returned Personnel Startup Fund: Genetic analysis of Glycogen Storage Disease Type I. 2001–2003 Qiu Zhengqing et al. (40,000).

7. Research fund from the Beijing Municipal Science and Technology Department: Study of human important functional genes encoding proteins and collection of genetic resources for major diseases—Subproject: Collection of resources and identification of pathogenic genes for autosomal dominant ectodermal dysplasia. 2002-2004 Wei Min et al. (200,000).

8. Capital Medical Development Research Fund: The impact of early feeding on gastrointestinal motility and gastrointestinal hormones in high-risk extremely low birth weight infants. 2003-2006 Ding Guofang et al. (100,000).

9. Research fund from Peking Union Medical College Hospital: Early prediction of allergic diseases in infants. 2003-2006 Wan Weilin et al. (40,000).

10. Research fund from Peking Union Medical College Hospital: The role of vitamin A in the prevention and treatment of patent ductus arteriosus in preterm infants. 2003-2006 Shen Jing et al. (40,000).

11. Research subproject on detection reagents for major human diseases: Study of matrix metalloproteinases in pediatric kidney diseases. 2003-2004 Song Hongmei et al. (30,000).

12. Hospital infection fund from Peking Union Medical College Hospital: Epidemiological investigation of NICU hospital infections and changes in antibiotic-related bacterial resistance. 2004-2006 Wang Danhua et al. (70,000).

13. Hospital infection fund from Peking Union Medical College Hospital: Early diagnosis of hospital infections in preterm infants. 2004-2006 Ding Guofang et al. (30,000).

(2) Participation in multicenter clinical studies:

Participated in five multicenter clinical studies nationwide and in Beijing.

(3) Publications and monographs:

1. Number of academic papers published in domestic core journals: 86.

2. Published academic monographs: 2.

3. Number of papers indexed by SCI, SSCI, EI: 3.

Century-Old Heritage · Premier Specialties

Academic Standing & Clinical Excellence

National-level referral center for pediatric critical care and rare diseases. The department has strong capabilities in treating pediatric rheumatic immune diseases, autoinflammatory diseases, genetic metabolic rare diseases, and critical care for neonates. It has independently developed a national class II new orphan drug, breaking the long-standing medication void for children with rare diseases such as glycogen storage disease in China.

National Centers & Research Platforms

  • 🏛Core unit of the National Collaborative Network for Pediatric Rare Disease Diagnosis and Treatment
  • 🏛Standing unit of the Pediatric Branch of the Chinese Medical Association
  • 🏛National-level Neonatal Critical Care Center
  • 🏛Key Laboratory for Pediatric Genetic Metabolism and Immunology

Core Indications & Conditions Treated

01Juvenile Idiopathic Arthritis (JIA), Pediatric Systemic Lupus Erythematosus, and Allergic Purpura
02Kawasaki Disease and Complications of Coronary Artery Lesions
03Pediatric Autoinflammatory Diseases (e.g., Periodic Fever Syndrome, Systemic JIA, etc.)
04Glycogen Storage Disease (GSD), Gaucher Disease, and other Genetic Metabolic Rare Diseases
05Pediatric Fever of Unknown Origin (FUO) and Complex Immune Deficiencies
06Critical Care for Extremely Low and Very Low Birth Weight Preterm Infants
07Bronchopulmonary Dysplasia (BPD) and Neonatal Respiratory Distress Syndrome
08Pediatric Refractory Diarrhea, Malnutrition, and Cow's Milk Protein Allergy

Clinical Strengths & Advanced Capabilities

Utilizing whole exome sequencing, in-depth immune function analysis, and multidisciplinary collaboration, we provide comprehensive care from etiological diagnosis and targeted therapy to long-term growth and development monitoring.

1

Rapid screening and specific biological agent targeted intervention for pediatric difficult immune and rare diseases through gene sequencing

2

Independently developed special formula therapy with raw corn starch and precision treatment with new orphan drugs for children with glycogen storage disease

3

Minimally invasive tracheal intubation medication delivery, high-frequency oscillatory ventilation, and fine enteral/parenteral nutritional support for neonates in the Neonatal Intensive Care Unit (NICU)

4

Multidisciplinary early screening and intervention for Retinopathy of Prematurity (ROP) and Periventricular Leukomalacia

5

Transition care for pediatric chronic diseases throughout the lifecycle, connecting to adult specialties

Lead Physicians & Specialists

21 Expert
SH

Song Hongmei

Chief Physician, Professor, Doctoral Supervisor

🏅 Former Chair of Pediatrics, PUMCH · Former Head of Immunology Group, Chinese Pediatric Society

Core Indications & Conditions Treated

Pediatric Rheumatologic Diseases (Juvenile Idiopathic Arthritis, Juvenile Lupus Erythematosus)Autoinflammatory Diseases and Periodic Fever in ChildrenGlycogen Storage Diseases and Other Rare Metabolic DisordersProlonged Fever of Unknown Origin in Children

National leader in pediatric rheumatology and rare diseases. Developed orphan drug therapeutics for glycogen storage diseases and specializes in pediatric autoinflammatory syndromes.

LZ

Li Zhenghong

Chief Physician, Professor, Doctoral Supervisor

🏅 Director of Pediatrics, PUMCH · Neonatal Medicine Specialist

Core Indications & Conditions Treated

Critical Care for Extremely Low Birth Weight Preterm InfantsNeonatal Respiratory Distress and Bronchopulmonary DysplasiaPediatric Gastroenterology and Clinical Nutritional SupportGrowth and Development Monitoring in Children

Director of Pediatrics at PUMCH, expert in neonatal intensive care (NICU) for extremely low birth weight infants, neonatal pulmonology, and clinical nutrition.

DM

Dong Mei

Chief Physician, Professor

Core Indications & Conditions Treated

Symptoms Manifesting as Abdominal DistensionAbdominal painAnorexiaNauseaVomitingDiarrhea

Dr. Dong Mei is a Chief Physician and Professor in pediatrics, specializing in gastrointestinal symptoms in children, including abdominal pain and anorexia.

DG

Ding Guofang

Chief Physician, Professor

Core Indications & Conditions Treated

Neonatal DiseasesEmergency Care and Management of Premature InfantsDiagnosis and Treatment of Neonatal JaundiceInfant Nutrition and FeedingDiagnosis and Treatment of Common Pediatric Internal Medicine Diseases

Dr. Ding Guofang is a Chief Physician and Professor in pediatrics, with expertise in neonatal diseases and emergency care for premature infants.

WM

Wei Min

Chief Physician, Professor, Doctoral Supervisor

Core Indications & Conditions Treated

Pediatric Kidney DiseasesHematuriaProteinuriaNephrotic SyndromeAcute GlomerulonephritisChronic Nephritis

Dr. Wei Min is a Chief Physician and Professor specializing in pediatric kidney diseases, particularly nephrotic syndrome and related conditions.

QZ

Qiu Zhengqing

Chief Physician, Professor

Core Indications & Conditions Treated

Hereditary Metabolic Liver DiseasesDiagnosis and Prenatal Diagnosis of Wilson's Disease and Related ConditionsDiagnosis and Consultation of Malformation SyndromesDiagnosis and Consultation for Pediatric Difficult Diseases

Dr. Qiu Zhengqing is a Chief Physician and Professor in pediatrics, focusing on hereditary metabolic liver diseases and the diagnosis of complex pediatric conditions.

WD

Wang Danhua

Chief Physician, Professor, Doctoral Supervisor

Core Indications & Conditions Treated

Nutrition for Premature InfantsDevelopmental Assessment and Early Intervention GuidanceInfant and Young Child NutritionGrowth and Development and Mental HealthNeonatal DiseasesGeneral Pediatric Internal Medicine Diseases

Dr. Wang Danhua is a Chief Physician and Professor specializing in nutrition for premature infants and developmental assessment in pediatrics.

HY

He Yanyan

Associate Chief Physician, Associate Professor

Core Indications & Conditions Treated

Diagnosis and Treatment of Pediatric Internal Medicine DiseasesDiagnosis and Treatment of Pediatric Primary and Secondary Kidney Diseases and Pediatric Rheumatic Immune Diseases

Dr. He Yanyan is an Associate Chief Physician and Associate Professor in pediatrics, specializing in pediatric internal medicine and kidney diseases.

WW

Wan Weilin

Chief Physician, Associate Professor

Core Indications & Conditions Treated

Diagnosis and Treatment of Pediatric Respiratory DiseasesChronic CoughObstructive BronchiolitisEosinophilic PneumoniaAllergic RhinitisWheezy Diseases in Infants and Young Children

Dr. Wan Weilin is an Associate Chief Physician and Associate Professor in Pediatrics, specializing in the diagnosis and treatment of pediatric respiratory diseases, including chronic cough and eosinophilic pneumonia.

XJ

Xiao Juan

Chief Physician, Professor, Doctoral Supervisor

Core Indications & Conditions Treated

Common and Complex Pediatric Internal Medicine DiseasesEspecially in Pediatric Hematologic and Oncologic DiseasesVarious Types of AnemiaIdiopathic Thrombocytopenic PurpuraAllergic PurpuraHemophilia

Dr. Xiao Juan is a Chief Physician and Professor in Pediatrics, with a focus on pediatric hematologic and oncologic diseases, particularly various types of anemia and idiopathic thrombocytopenic purpura.

BX

Bao Xiulan

Chief Physician, Professor

Core Indications & Conditions Treated

Pediatric Endocrinology Clinic for Short StaturePituitary DwarfismAssessment of Neonatal Behavior and Its ApplicationsEarly Education for Children Aged 0-3 and Choking in InfantsEarly Intervention for Premature InfantsCerebral Palsy

Dr. Bao Xiulan is a Chief Physician and Professor in Pediatrics, specializing in pediatric endocrinology and early childhood development.

WC

Wang Chen

Associate Chief Physician

Core Indications & Conditions Treated

Neonatal DiseasesPediatric Health Care

Dr. Wang Chen is an Associate Chief Physician in Pediatrics, with a focus on neonatal diseases and pediatric health care.

MM

Ma Mingsheng

Associate Chief Physician

Core Indications & Conditions Treated

Genetic DiseasesWilson's DiseaseGlycogen Storage DiseasesLysosomal DiseasesRheumatic and Autoimmune DiseasesJuvenile Idiopathic Arthritis

Dr. Ma Mingsheng is an Associate Chief Physician specializing in pediatric genetic diseases, including Wilson's disease and glycogen storage diseases.

JS

Jian Shan

Associate Chief Physician, Associate Professor

Core Indications & Conditions Treated

Pediatric Renal DiseasesRheumatic and Immune DiseasesDiagnosis and Treatment of Neonatal Diseases and Complex ConditionsEspecially in the Field of Glomerular DiseasesLupus NephritisHenoch-Schönlein Purpura Nephritis

Dr. Jian Shan is an associate chief physician and associate professor in pediatrics, focusing on pediatric renal diseases and rheumatic conditions. She has a strong clinical background and has participated in advanced training in pediatric nephrology.

LJ

Li Ji

Associate Chief Physician

Core Indications & Conditions Treated

Systemic Lupus ErythematosusJuvenile Idiopathic ArthritisMilk Protein AllergyShort Stature in ChildrenChild Growth and Development and Pediatric Health CareImmune Thrombocytopenic Purpura

Dr. Li Ji is an associate chief physician in pediatrics, with expertise in systemic lupus erythematosus and juvenile idiopathic arthritis. He has published extensively and is involved in teaching and mentoring graduate students.

TX

Tang Xiaoyan

Associate Chief Physician

Dr. Tang Xiaoyan is an associate chief physician in pediatrics, specializing in gastrointestinal disorders in children. He has significant experience in diagnosing and treating rare metabolic diseases.

ZZ

Zhang Zhenjie

Attending Physician

Core Indications & Conditions Treated

Common Pediatric DiseasesMultiple diseasesAbility to Flexibly Apply Cutting-edge Knowledge from Home and Abroad to Solve Clinical Problems

Dr. Zhang Zhenjie is an Attending Physician in the Department of Pediatrics, with a focus on common pediatric diseases and the application of cutting-edge knowledge to solve clinical problems.

YZ

Yu Zhongxun

Resident Physician

Core Indications & Conditions Treated

Pediatric Autoimmune DiseasesMonogenic Autoinflammatory DiseasesType I Interferonopathies

Dr. Yu Zhongxun is a resident physician specializing in pediatric autoimmune diseases and monogenic autoinflammatory diseases.

LY

Li Yunwei

Attending Physician

Dr. Li Yunwei is an attending physician in the Pediatrics Department at Peking Union Medical College Hospital, focusing on pediatric care.

JJ

Jiang Jingjing

Attending Physician

Core Indications & Conditions Treated

Neonatal DiseasesCommon Pediatric DiseasesDifficult Diseases

Dr. Jiang Jingjing is an attending physician in the Pediatrics Department at Peking Union Medical College Hospital, specializing in neonatal diseases and common pediatric conditions.

ZY

Zhou Yu

Attending Physician

Core Indications & Conditions Treated

Pediatric Rheumatologic and Autoinflammatory Diseases

Dr. Zhou Yu is an attending physician specializing in pediatric rheumatologic and autoinflammatory diseases.

Request support

Independent support for patients seeking care at PUMCH

Century-Old Heritage · Premier Specialties

Department of Pediatrics · Request support

Request support